Previously, I wrote about Phase I detoxification genetics and how your very own genes determine your strengths and weaknesses in removing toxins (not unlike the genetic polymorphisms in the X-Men series). Click here for the Phase I detox rundown. Now it’s time to understand what happens when Phase II detoxification begins.
Basically, Phase I breaks down toxins part of the way and Phase II finishes the job. Once Phase II has worked its magic, the body can remove the offending substances from the body through the colon or urinary tract.
There are four areas of clearing: Methylation, Acetylation, Glutathione Conjugation, and Oxidative Protection. Since the test speaks for itself, I invite you to peruse the results below.
Genova Diagnostics reports that this test has not been cleared or approved by the FDA. Nor do they claim this test is 100% perfectly accurate. Just as in many scientific tests, there is the chance of false negatives. In their words, “Negative findings do not imply that your patient is risk-free.”
However, getting your own results can help you understand where some of your “weak links” reside. In the above example, the plus minus result for NAT2 R197Q explains why this person should never smoke. The risk of lung cancer is substantially higher in someone with compromised NAT activity. Have you ever wondered why some people smoke their whole lives without it affecting their health while others end up with lung cancer and emphysema? It’s all in their toxin removal genetics.
Another interesting example is found in the COMT gene results. This patient has a polymorphism in this area. COMT stands for catechol-O-methyltransferase, which inactivates catecholamines and catechol estrogens. A reduced ability to degrade these compounds can lead to some neuropsychiatric disorders, impaired estrogen metabolism, and increased sensitivity to pain. But this person is not without hope. To combat this weakness, the patient needs to ensure adequate intake of B vitamins, magnesium, and protein. All of which are easily done once the patient understands the necessity of these nutrients.
If you want to learn more about your own genetics – and how to strengthen your weak links, you can find a doctor who is trained in these tests and qualified to order them for you at: http://www.gdx.net/patients/practitioner-directory
After you support your weakest points, you may find a whole new world of health awaiting you. Knowledge is power!
Hey, thanks for the great post. I feel better after having read this.